Table 5. The MICs and FICs of individual agents in the combination treatments of CDots with AcOH, and the total FICs of combination treatments, obtained using the microdilution checkerboard method.
Combination Treatments | FIC of CDots | FIC of AcOH | ΣFIC | |
---|---|---|---|---|
CDots (μg/mL) | AcOH (%) | |||
64 (MIC) | 0 | - | - | - |
64 | 0.000625 | 1 | 0.015625 | 1.015625 |
64 | 0.00125 | 1 | 0.03125 | 1.03125 |
64 | 0.0025 | 1 | 0.0625 | 1.0625 |
64 | 0.005 | 1 | 0.125 | 1.125 |
64 | 0.01 | 1 | 0.25 | 1.25 |
64 | 0.02 | 1 | 0.5 | 1.5 |
0 | 0.04 (MIC) | - | - | - |
0.5 | 0.04 | 0.0078125 | 1 | 1.0078125 |
1 | 0.04 | 0.015625 | 1 | 1.015625 |
2 | 0.04 | 0.03125 | 1 | 1.03125 |
4 | 0.04 | 0.0625 | 1 | 1.0625 |
8 | 0.04 | 0.125 | 1 | 1.125 |
16 | 0.04 | 0.25 | 1 | 1.25 |
32 | 0.04 | 0.5 | 1 | 1.5 |