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In the small intestine the relative expression of HD5 (p = 0.004), HD6 (p = 0.006) and Reg3α (p = 0.012) was significantly decreased (Mann-Whitney-U-Test) in case of severe acute GvHD (stage 2–4) (3A). Patients with acute intestinal GvHD stages 2–4 showed an increase in expression of HD5 (p<0.001), HD6 (p<0.001) and Reg3α (p = 0.002) in the large intestine (Mann-Whitney-U-Test) (3B).
