Skip to main content
. 2017 Sep 11;11(9):e0005846. doi: 10.1371/journal.pntd.0005846

Table 2. Adjusted spot counts from ex-vivo IFN-γ ELISpot at each time point.

Adjusted spot count (SFC/106 PBMC)
Days after infection Control macaques (n = 5) O. tsutsugamushi infected macaques (n = 10)
1 2 3 4 5 Mean 6 7 8 9 10 11 12 13 14 15 Mean
Day 0 7.5 12.5 7.5 12.5 32.5 14.5 0 15 2.5 12.5 10 12.5 7.5 17.5 15 25 11.75
Day 7 2.5 22.5 10 0 12.5 9.5 262.5 232.5 192.5 252.5 262.5 212.5 240 302.5 267.5 125 235
Day 14 7.5 30 0 0 55 18.5 1250 1392.5 1500 1500 997.5 1342.5 1245 1497.5 882.5 1005 1261.25
Day 21 0 27.5 0 0 22.5 10 1497.5 1500 1500 1495 1500 1500 1492.5 1497.5 1497.5 1500 1498
Day 28 22.5 25 7.5 15 0 14 1497.5 1500 1497.5 1577.5 1080 1480 1480 1310 1247.5 1495 1416.5

Values represent the mean SFC/106 PBMC count from cellular immune responses to OT-WCA after subtraction of the background response (complete media) after ID administration of live O. tsutsugamushi (n = 10) versus mock (n = 5) in rhesus macaques.