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hpAP-1 cODN (hpAP1c), but Not the Mutated Control ODN (hpAP1m), Significantly Decreases the IL-1β-Induced Accumulation of ROS in mgR/mgR SMCs
(A) Analysis of cellular ROS production by DCF-DA stainings using confocal microscopy; scale bar corresponds to 25 μm. (B) Quantification of mean fluorescence intensity of DCF as a measure of oxidative stress. (*p = 0.0152 hpAP1c versus IL-1β-stimulated group; #p < 0.0001, hpAP1c versus hpAP1m, n = 4, one-way ANOVA).
