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. 2017 Sep 20;19(11):896–907. doi: 10.1016/j.neo.2017.08.009

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Nilotinib treatment leads to increased vessel sprouting. Representative TPLSM images of tumors from the different treatment groups at day 14 show the irregular vascular network with various branching points in the control, nilotinib, and combined treatment group. The nilotinib-treated tumor displays the highest vessel density and number of branch points. In the DC101-treated group, vessel density and the amount of branches are strongly reduced. Perfused vessels in green, scale bar: 50 μm.