Fig. 3.
Overexpression of human Nox4DN in endothelium increases arterial stiffness and type I diabetes induced atherosclerotic lesions. A. Representative picture of Oil Red O (ORO) staining of aortic root lesions at 6 weeks after type I diabetes was induced (20×). Quantification in graph. *p < 0.05 vs. ApoE−/−, #p < 0.05 vs. vehicle control, n = 8–17. B. Pulse wave velocity (PWV) at 4 weeks after type I diabetes was induced. *p < 0.05 vs. ApoE−/−, n = 6. C. Representative picture of carotid artery lesions 2 weeks after partial LCA ligation with 6 weeks of type I diabetes induction (20×). Quantification in graph. *p < 0.05 vs. ApoE−/−, #p <| 0.05 vs. vehicle control, n = 9–12.