Figure 2.

Histological and immunohistochemical analyses of preneoplastic lesions and mammary tumors in the Lfng^flox/flox;p53^flox/+;MMTV-Cre mice. (A-C) Representative photomicrographs of H&E stained mammary gland sections at 2 months of age. (D-F) Representative photomicrographs of H&E stained mammary tumor sections. (G-L) Representative photomicrographs of immunostaining in mammary tumors. Insets: high-magnification images of Notch nuclear staining. Percentage of positively stained cells are quantitated and presented as mean ± standard deviation. Scale bars: 50 μm.