Table 4.
Comparison of the secondary outcomes.
| Hemodynamic parameters, maximum change |
Ketofol, n = 55 Median (IQR) [95% CI] |
Etofen, n = 57 Median (IQR) [95% CI] |
Significance |
|---|---|---|---|
| SBP, mmHg | 20 (20, 30) [20.00, 22.36] |
−10 (−10, −3) [−10.00, −5.00] |
<0.001 |
| DBP, mmHg | 15 (10, 20) [10.00, 20.00] |
−5 (−10, 0) [−6.84, 0.00] |
<0.001 |
| MAP, mmHg | 16.67 (13.33, 20.00) [13.33, 20.00] |
−6.67 (−10.00, 0.42) [−10.00, 3.33] |
<0.001 |
| HR, bpm | 8 (7.25, 10.00) [8.00, 9.00] |
−2 (−6, 4) [−4.00, 2.00] |
<0.001 |
| RR, rpm | 1 (−2, 2) [−1.00, 2.00) |
−2 (−2.00, 0.25) [−2.00, −1.00] |
0.0013 |
| pSO2, % | −1 (−9, 0) [−7.24, −1.00] |
0 (−1, 1) [−1, 0] |
0.0019 |
| ETCO2, % | 8 (5, 10) [6.00, 9.00] |
2 (−1, 4) [2.00, 4.00] |
<0.001 |
| Sedation duration, min | 18 (16.25, 19.75) [18, 19] |
8 (4, 12) [6, 10] |
<0.001 |
| Ramsey Sedation Score | 5 (5, 6) [5, 6] |
4 (4, 4) [4, 4] |
<0.001 |
| Pain, pre (VAS, cm) | 9 (8, 9) [9, 9] |
8 (8, 9) [8, 9] |
<0.001 |
| Pain, post (VAS, cm) | 3 (2.25, 4) [3, 3] |
2 (2, 3) [2, 2] |
<0.001 |
| VAS decrease | −6 (−6, −5) [−6, −5.76] |
−6 (−7, −5) [−7, −6] |
0.0926 |
| Physician Satisfaction Score | 8 (7, 10) [8, 9] |
8 (7, 8) [7.63, 8.00] |
0.0269 |
P values by Mann-Whitney U test.