Table 1.
Characteristics of the ROS and MAP participants included in analyses
| Variable | MAP n=438 | ROS n=471 | p-value |
|---|---|---|---|
| age at death | 89.4 ± (5.8) | 87.5 ± (6.9) | <.0001 |
| Male | 151 (34%) | 174 (37%) | 0.480 |
| Pathology dx of AD* | 275 (63%) | 295 (63%) | >0.99 |
|
| |||
| Pathology | |||
|
| |||
| Lewy Body | 87 (20%) | 108 (23%) | 0.296 |
| Neurofibrillary Tangles | 0.70 ± (0.41) | 0.66 ± (0.41) | 0.171 |
| Neuritic Plaque | 0.74 ± (0.53) | 0.74 ± (0.54) | 0.993 |
| Diffuse Plaque | 0.64 ± (0.48) | 0.71 ± (0.50) | 0.029 |
| Micro Infarct | 113 (26%) | 140 (30%) | 0.213 |
| Macro Infarct | 162 (37%) | 165 (35%) | 0.586 |
| CAA** | 0.272 | ||
| None | 78 (18%) | 105 (22%) | |
| Mild | 204 (47%) | 200 (42%) | |
| Moderate | 105 (24%) | 104 (22%) | |
| Severe | 51 (12%) | 62 (13%) | |
*
NIA-Reagan Criteria,
**
CAA - Cerebral Amyloid Angiopathy