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. Author manuscript; available in PMC: 2017 Nov 22.
Published in final edited form as: Oncogene. 2017 May 22;36(38):5421–5431. doi: 10.1038/onc.2017.143

Figure 2. Group I Pak inhibitors reduce MPNST cell proliferation and invasion.

Figure 2

A. Suppressive effect of peptide PAK1/2/3 inhibitor GST-PID on iHSC, ST8814, STS26T and S462TY cell growth. B. Dose response to a small molecule PAK1/2/3 inhibitor Frax1036 in iHSC and MPNST cells. C. Invasiveness of iHSC and MPNST cells treated PAK1/2/3 inhibitors determined by trans-matrigel invasion assay. Error bars represent standard deviation (*= p<0.05, **= p<0.01, ***= p<0.005).