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. 2017 Mar 21;23(4):1001–1013. doi: 10.1038/mp.2017.15

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Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Enrichment of maternal immune activation (MIA)-downregulated genes with classes of autism spectrum disorder (ASD)-associated genes and ASD cortical transcriptome downregulated genes. This figure describes MIA-downregulated genes and their enrichment within different classes of ASD-associated genes and genes that downregulated in the ASD cortical transcriptome. Panel a shows process level enrichments for all MIA-downregulated genes. Panel b shows enrichment odds ratios for different classes of ASD-associated genes (the * indicates enrichment passing false discovery rate (FDR) q<0.05, while the ~ indicates enrichment passing FDR q<0.1). Panels c and d show enrichment between downregulated genes in MIA and ASD cortical transcriptome datasets (panel c for the Voineagu dataset and panel d for the Gupta dataset). Panels e and f show process level enrichments for the common downregulated genes between MIA and ASD (panel e for the Voineagu dataset and panel f for the Gupta dataset).