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. 2017 Mar 21;23(4):1001–1013. doi: 10.1038/mp.2017.15

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Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Cross-species validation of dysregulated gene expression within the Tsc1/2–mTor–Eif4ebp1/2 axis in a mouse MIA model. This figure summarizes the results from qRT-PCR analysis of gene expression along the Tsc1/2–mTor–Eif4ebp1/2 axis hypothesized to show dysregulation from the previous rat model data. Each gene is displayed with a scatter-boxplot and gene expression for each individual sample is plotted on the y-axis as % mRNA expression normalized to the average value in the SAL condition. Boxplots show the median and interquartile range (IQR; Q1=25th percentile, Q3=75th percentile), as well as the outer fences (Q1 – (1.5IQR) and Q3+(1.5IQR)). MIA, maternal immune activation; SAL, saline.