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. 2017 Sep 21;7:12084. doi: 10.1038/s41598-017-12360-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene expression profiling revealed induction of cell adhesion pathways and reduced expression of genes involved in chemotaxis. (a) Heat map of a sample-to-sample Pearson correlation and dendrogram showing sample-to-sample correlation. All biological replicates cluster well with each other, and all samples from different populations are clearly separated from each other (analysis by R). (b) The red dots represent differentially expressed genes (DEG) by VPA treatment (1% false discovery rate). (c,d) GO pathway analysis for differentially expressed genes. Plots show biological processes that are associated with genes that are up- or down-regulated in VPA treated CD34⁺ cells.