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. 2017 Sep 21;7:12064. doi: 10.1038/s41598-017-10924-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of cannabidiol on alcohol-induced NAD(P)H oxidase isoforms mRNA and protein expression in the liver. Levels of NAD(P)H oxidase isoform NOX2/gp91phox (A) and p67phox (B) mRNA were analyzed by real-time PCR. The results are expressed as fold increases relative to the pair-fed group. Values represent means ± SEM (n = 5–7). *P < 0.05 vs. Pair-fed group, ^# P < 0.05 vs. EtOH group determined by One-way ANOVA, followed by Tukey’s post-hoc test. (C) Western blot analyses of gp91phox with loading control β-actin. The full-length blots are included in the Supplemental information file.