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. 2017 Sep 21;7:12107. doi: 10.1038/s41598-017-11690-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Protein abundance distribution over the cellular sub-fractions in hippocampus (HC), cortex (CT) and cerebellum (CB). Left panel is an immunoblot analysis showing the presence of presynaptic protein SYP, and postsynaptic proteins GRIN2A and DLG4 in each sub-fraction. Right panel shows protein abundance in each sub-fraction as observed with proteomics. Mass spectrometry protein abundance values were scaled between zero and 100% of their maximum over all sub-fractions in each panel and accordingly color-coded from light-blue to dark-blue.