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. 2017 Sep 21;7:12075. doi: 10.1038/s41598-017-12458-5

Figure 2.

Figure 2

Amino acid variation in the capsid-encoding region of a subset of HPeV3 isolates. (a) Alignment showing the positions of variable amino acid residues. Capsid surface-exposed residues are highlighted in red. (b) HPeV3 roadmap of capsid exterior. Five full asymmetric units are shown; each formed of one copy of capsid proteins VP0 (blue), VP3 (green) and VP1 (pink). The AT12-015 Fab footprint (yellow contour) is mapped on surface residues differing between the strains (red), in comparison to the prototype A308/99. Residue-labeled close-up roadmaps for each strain are showed in Supplementary Information 1.