Table 3.

Summary of meta-analysis and GRADE assessments of quality of data

outcome measure	number of studies (pooled sample)	Heterogeneity		Total effects		Measure compared	95%CI	GRADE result
		I2	p	Z	p
Cognition	5(1278)	88%	<0.00001	0.57	0.57	SMD=-0.1	[-0.46,0.25]	moderate
Negative symptoms	8(1438)	64%	0.002	1.52	0.13	SMD=0.13	[-0.04,0.30]	Moderate
Adverse events	4(1212)	49%	0.12	0.20	0.84	OR=1.02	[0.85, 1.23]	high
Dropouts rates	4(1212)	0%	0.87	0.15	0.88	OR=1.04	[0.61, 1.78]	high