Table 4.
Odds ratios for obesity and abdominal obesity Differentially Methylated Positions (DMPs)
| Obesity | Abdominal obesity | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CpG | CHR | Position | Genea | Featureb | ORc | 95% CI | Attributable trait variance (%) | ORc | 95% CI | Attributable trait variance (%) |
| cg07839457 | 16 | 57023022 | NLRC5 | TSS1500 | 1.04 | 1.02–1.06 | 2.4 | 1.03 | 1.01–1.06 | 1.4 |
| cg00574958 | 11 | 68607622 | CPT1A | 5′ UTR | 0.85 | 0.80–0.91 | 6.1 | 0.84 | 0.79–0.90 | 5.6 |
| cg20399616 | 12 | 25055967 | BCAT1 | Body | 0.94 | 0.90–0.98 | 1.6 | 0.96 | 0.91–1.00 | 0.7 |
aCpGs are located in the gene if no distance is indicated
bBased on manifest feature annotation Illumina
cOdds ratios are per 1% increase in DNA methylation