Table 2.
Results of other potential covariates in ALS patients between different HbA1c status (N = 450)
| HbA1c, % | <5.7 | 5.7–6.4 | ≥6.5 | P-trend |
|---|---|---|---|---|
| Number | 263 | 152 | 35 | |
| BMI, kg/m2 | 22.3(3.3) | 22.0(3.0) | 22.7(3.1) | 0.57 |
| BMI status | ||||
| Normal, % | 84.8 | 86.2 | 82.9 | 0.79 |
| Overweight, % | 14.4 | 13.8 | 17.1 | |
| Obesity, % | 0.8 | 0.0 | 0.0 | |
| Smoking, % | 32.3 | 29.6 | 31.4 | 0.85 |
| Alcohol drinking, % | 32.7 | 26.3 | 25.7 | 0.33 |
| Hypertension, % | 11.8 | 19.7 | 17.1 | 0.08 |
| Anemia, % | 7.2 | 5.3 | 8.6 | 0.67 |
| Erythrocytes, 10^12/L | 4.5(0.5) | 4.6(0.5) | 4.7(0.5) | 0.003 |
| Platelets, 10^9/L | 164.1(54.9) | 171.8(55.9) | 193.6(58.0) | 0.01 |
| Total leukocytes, 10^9/L | 5.6(1.4) | 5.9(2.0) | 7.0(2.9) | <0.001 |
| Neutrophils, 10^9/L | 3.4(1.2) | 3.7(1.8) | 4.5(2.2) | 0.001 |
| Lymphocytes, 10^9/L | 1.6(0.5) | 1.7(0.5) | 2.0(0.8) | 0.001 |
| Monocytes, 10^9/L | 0.3(0.1) | 0.4(0.1) | 0.4(0.2) | <0.001 |
| Triglyceride, mmol/L | 1.4(0.9) | 1.4(0.7) | 2.2(1.8) | <0.001 |
| Total Cholesterol, mmol/L | 4.5(0.8) | 4.8(0.9) | 5.0(1.2) | <0.001 |
| Use of hypoglycemic agents, % | 0.0 | 0.0 | 60.0 | <0.001 |
Abbreviations: ALS amyotrophic lateral sclerosis, HbA1c Hemoglobin A1c, BMI body mass index