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. 2017 Jul 9;14(3):2255–2260. doi: 10.3892/etm.2017.4729

Figure 1.

Figure 1.

Hesperetin improves cardiac function in MI mice. (A) LVEF and (B) LVFS decreased in the Vehicle-MI group 8 weeks after left anterior descending coronary artery ligation surgery; however, the Hesperetin-MI group displayed better cardiac function. The mRNA levels of (C) ANP and (D) BNP in the hearts of mice following Sham or MI surgery with or without hesperetin treatment. The Vehicle-MI group showed an increase in the mRNA levels of ANP and BNP compared with those in the Vehicle-sham group, which was significantly reduced by hesperetin. Values are expressed as the mean ± standard deviation. *P<0.05 vs. Vehicle-sham group; #P<0.05 vs. Hesperetin-sham group; &P<0.05 vs. Vehicle-MI group. LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide; MI, myocardial infarction.