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. 2017 Jul 9;14(3):2255–2260. doi: 10.3892/etm.2017.4729

Figure 2.

Figure 2.

Hesperetin reduces inflammatory responses in MI mice. The mRNA levels of inflammatory cytokines (A) TNF-α, (B) IL-1β and (C) IL-6 in the hearts of mice following Sham or MI surgery with or without hesperetin treatment. The levels of inflammatory cytokines (D) TNF-α, (E) IL-1β and (F) IL-6 in the serum of the indicated groups determined by ELISA. Compared with those in the Vehicle-sham group, the Vehicle-MI group displayed a higher increase in the levels of TNF-α, IL-1β and IL-6 than the Hesperetin-sham group. Values are expressed as the mean ± standard deviation. *P<0.05 vs. Vehicle-sham group; #P<0.05 vs. Hesperetin-sham group; &P<0.05 vs. Vehicle-MI group. MI, myocardial infarction; TNF, tumor necrosis factor; IL, interleukin.