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. 2017 Jul 10;14(3):2216–2220. doi: 10.3892/etm.2017.4763

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Copyright: © Xu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of esculetin against DOX-induced Bmi-1 expression in H9c2 cells. (A) Effects of esculetin on Bmi-1 expression in DOX-induced H9c2 cells, compared with the DOX (**P<0.01). (B) Effects of Bmi-1 siRNA on Bmi-1 expression in each group. (C) Effects of Bmi-1 siRNA on cell apoptosis in each group. (D) Effects of Bmi-1 siRNA on ROS levels in each group, compared with the blank siRNA group (**P<0.01). DOX, doxorubicin; ROS, reactive oxygen species.