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. 2017 Jul 9;14(3):2310–2316. doi: 10.3892/etm.2017.4741

Figure 4.

Figure 4.

EPA pretreatment improves cardiac ion channel expression in rapidly-paced atria. The expression levels of the K+ ion channel genes, Kcnd2, KChIP2 and Kcna5, increased after pacing in the control group and both EPA and pitavastatin pretreatment attenuated this effect. EPA and pitavastatin also suppressed the expression of Slc9a1; however, rapid pacing did not significantly influence its expression in the control group. Expression levels are relative to GAPDH. Data are presented as the mean + standard error of the mean. #P<0.05 and *P<0.01 as indicated. EPA, eicosapentaenoic acid; Kcnd2, potassium voltage-gated channel subfamily D member 2; KChIP2, Kv channel-interacting protein 2; Kcna5, potassium voltage-gated channel subfamily A member 5; Slc9a1, solute carrier family 9 member A1.