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. 2017 Aug 22;10(5):1120–1127. doi: 10.1111/1751-7915.12790

Table 2.

Some approaches to increase photofermentation H productivity (Reviewed by Adessi et al., 2017)

Approach/Rationale Outcomes/comments References
‘Black box’ mathematical relationships between input and output streams Box‐behnken statistical design/methods Permits multivariable analysis: measures cause and effect; hence can be empirical SCE (glycerol) > doubled (R.palustris) Abo‐Hashesh et al. (2013), Show and Lee (2013) and Ghosh et al. (2012a,b,c)
Modelling metabolic fluxes Guided interventions: success using lactate but not malate or acetate Golomysova et al. (2010) and Hädicke et al. (2011)
Deletion of polyhydroxybutyrate synthesis pathway Increased H2 yield (by 1.5‐fold c.f. wild type) Kim et al. (2011)
Reducing pigment concentration Allows greater light penetrationa Ma et al. (2012)
Use of quantum dots to ‘upgrade’ light Doubled photosynthetic efficiency M.D. Redwood, unpublishedb

SCE, substrate conversion efficiency.

a

27% increase in H2 yield was obtained.

b

Collaborative study with Photon Science Institute, University of Manchester: M.D. Redwood, L.E. Macaskie and D.J. Binks, unpublished work. But note: current commercial quantum dots would be grossly uneconomic at scale.