. Author manuscript; available in PMC: 2018 Apr 1.

Published in final edited form as: JACC Clin Electrophysiol. 2016 Dec 21;3(4):353–363. doi: 10.1016/j.jacep.2016.10.011

TABLE 1.

Electrocardiogram and AP Parameters in Epicardial Ablation Experiments

	Control	Provocative Agents	Epicardial Ablation
NS5806 + verapamil^*
J-wave area_r	3.07 ± 1.04	42.68 ± 5.77^†	5.11 ± 1.06^‡
T_peak-T_end, ms	30.53 ± 5.27	115.27 ± 7.05^†	45.18 ± 2.43^‡
AP notch area_r	4.74 ± 2.10	60.05 ± 5.24^†	18.19 ± 2.88^‡
EDR, ms	3.6 ± 1.24	150.25 ± 18.74^†	36.38 ± 17.18^‡
TDR, ms	11.38 ± 3.76	107.4 ± 14.91^†	23.4 ± 12.82^‡
Pinacidil + ajmaline^§
J-wave area_r	2.90 ± 0.48	26.75 ± 1.83^†	5.61 ± 3.28^‡
T_peak-T_end, ms	28.65 ± 4.61	95.38 ± 9.21^†	31.55 ± 11.99^‡
AP notch area_r	9.38 ± 2.25	54.90 ± 14.93^†	4.56 ± 0.90^‡
EDR, ms	8.1 ± 5.64	106.2 ± 20.49^†	12.4 ± 9.5^‡
TDR, ms	12.33 ± 3.44	65.55 ± 18.17^†	4.43 ± 2.49^‡
All^∥
J-wave area_r	3.0 ± 0.63	36.31 ± 4.28^†	5.31 ± 1.35^‡
T_peak-T_end, ms	29.78 ± 3.48	107.31 ± 6.2^†	39.73 ± 5.11^‡
AP notch area_r	6.6 ± 1.65	57.99 ± 6.29^†	12.74 ± 2.79^‡
EDR, ms	5.4 ± 2.3	132.63 ± 14.99^†	26.79 ± 11.21^‡
TDR, ms	11.76 ± 2.51	90.66 ± 12.84^†	15.81 ± 8.07^‡

Values are s mean ± SEM.

n = 6.

^†

p < 0.05 versus control.

^‡

p < 0.05 versus pre-ablation.

^§

n = 4.

^∥

n = 10.

AP = action potential; EDR = epicardial dispersion of repolarization; TDR = transmural dispersion of repolarization; T_peak-T_end = T wave peak-to-end duration.