Table 1. Enzymes, their abbreviations, their human counter targets, reference PDB used for analysis and inhibitors for twelve enzyme targets.

S.No	Enzyme	Abb	Human counter targets		Ref PDB	Substrates or compounds/ Speciesa
			Presence	PDB
1	Acetyl-coenzyme A carboxyl transferase beta chain	AccC	Distant homolog: domain of FasN	1XKT (FASN), 5I87 (Acc2)	2V58 E. coli	Biotin, Adenine
2	Beta-ketoacyl-acyl carrier protein synthase III	FabH	Distant homolog: domain of FasN	NA	1MZS E. coli	Ceruleninpar (Saccharomyces cerevisiae)
3	Enoyl-[acyl-carrier-protein] reductase [NADH]	FabI	None	NA	1QSG E. coli	Triclosan (Staphlococcus aureus)
4	Dihydrofolate reductase	Fol A	Distant homolog of DHFR	4QHV	4NX6 E. coli	Isoniazid (M. tuberculosis), Proguanil (Plasmodium falciparum) Methotrexate
5	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	Fol K	None	NA	4M5H E. coli	Aminosalicylic acid (M. tuberculosis)
6	1-deoxy-D-xylulose 5-phosphate synthase	Dxs	None	NA	2EGH E. coli	–
7	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	IspH	None	NA	3ZGL E. coli	–
8	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Dxr	None	NA	4NAL E. coli	–
9	D-alanine–D-alanine ligase	ddlB	None	NA	1IOW E. coli	Cycloserine (M. tuberculosis)
10	6,7-dimethyl-8-ribityllumazine synthase	ribH	None	NA	2VI5 M.tuberculosis	–
11	Nicotinate-nucleotide adenylyltransferase	NADD	Distant homolog, NMNAT	1KR2	1K4M E. coli	Niacin
12	Phosphopantetheine adenylyltransferase	CoaD	Distant homolog domain of PPAT/DPCK bifunctional enzyme	3DO8 (Closer homolog of Human)	1B6T E. coli	–

Notes.

Abb, abbreviation.

^aAs found in Drugbank.