Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 19;4:42. doi: 10.3389/fnut.2017.00042

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Vecchione, Grasselli, Cioffi, Baldini, Oliveira, Sardão, Cortese, Lanni, Voci, Portincasa and Vergani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of silybin on mitochondrial oxygen consumption rates (OCRs). Under the conditions of Figure 1, we measured the cellular OCR by using Seahorse XFe96 Extracellular Flux Analyzer. The following respiratory parameters were evaluated: (A) Cell basal respiration (OCR pmol/min/SRB labeling). (B) Proton leak (OCR pmol/min/SRB labeling). (C) Cell maximal respiration (OCR pmol/min/SRB labeling); (D) ATP production (OCR pmol/min/SRB labeling). Data are expressed as mean ± SD of 14 separate experiments. ANOVA followed by Tukey’s test was used to assess the statistical significance between groups. Significant differences are denoted by symbols: Ctrl vs all treatments ***p ≤ 0.001, *p ≤ 0.05; SS vs all treatments, ^#p ≤ 0.05; SH vs all treatments ^$$$p ≤ 0.001.