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Characterization of nanoparticles
| Nanoparticles | Size (nm) | Zeta potential (mV) | PDI | Drug loading (%) | EE (%) |
|---|---|---|---|---|---|
| Sali-NP | 123.2±14.1 | −25.6±4.2 | 0.12±0.06 | 8.8±2.7 | 59.2±9.3 |
| Sali-NP-HER2 | 135.6±17.6 | −28.3±5.8 | 0.15±0.03 | 8.0±3.9 | 55.4±8.5 |
Note: Data are expressed as mean ± SD (n=3).
Abbreviations: EE, encapsulation efficacy; PDI, polydispersity index; Sali-NP, salinomycin-loaded polymer–lipid nanoparticles; Sali-NP-HER2, salinomycin-loaded polymer–lipid hybrid anti-HER2 nanoparticles.
