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IC20 values for ACA and its analogs on MDA-MB-231 cell line
| IC20 (μM)
| |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ACA | 2 | 5 | 6 | 7 | 8 | AEA | AMCA | 19 | 20 |
| 2.0 | 48.0 | 32.0 | 50.0 | 31.0 | 50.0 | 4.0 | 12.0 | 28.0 | 45.0 |
Note: IC20 for each analog was used to treat MDA-MB-231 cells for wound-healing assay.
Abbreviations: ACA, 1′S-1′-acetoxychavicol acetate; AEA, 1′-acetoxyeugenol acetate; AMCA, 1′-acetoxy-3,5-dimethoxychavicol acetate; IC20, 20% inhibitory concentration.
