Table 2.
Physician Perceived High Risk (N=111) | Physician Perceived Low Risk (N=50) | Patient Perceived High Risk (N=23) | Patient Perceived Low Risk (N=138) | |
---|---|---|---|---|
Vital Signs | ||||
Weight (kg) | 93 ± 26 | 90 ± 24 | 92 ± 29 | 92 ± 25 |
Height (cm) | 173 ± 10 | 171 ± 10 | 175 ± 10 | 172 ± 10 |
Body Mass Index (kg/m2) | 31 ± 8 | 31 ± 9 | 29 ± 8 | 31 ± 8 |
Heart rate (beats per minute) | 80 ± 15 | 79 ± 14 | 79 ± 13 | 80 ± 15 |
Systolic blood pressure (mmHg) | 109 ± 67 | 114 ± 19* | 104 ± 14 | 112 ± 15† |
Diastolic blood pressure (mmHg) | 67 ± 10 | 70 ± 11 | 63 ± 8 | 69 ± 11† |
Laboratory Values | ||||
Sodium (mmol/L) | 137 ± 4 | 137 ± 4 | 136 ± 4 | 138 ± 4 |
Potassium (mEq/L) | 4.1 ± 0.5 | 4.2 ± 0.5 | 4.2 ± 0.5 | 4.1 ± 0.5 |
Blood urea nitrogen (mg/dL) | 38 ± 22 | 28 ± 13* | 39 ± 24 | 34 ± 19 |
Creatinine (mg/dL) | 1.6 ± 0.7 | 1.4 ± 0.5* | 1.4 ± 0.5 | 1.5 ± 0.6 |
Alanine aminotransferase (u/L) | 30 ± 32 | 43 ± 60 | 31 ± 23 | 35 ± 45 |
Aspartate aminotransferase (u/L) | 30 ± 14 | 38 ± 37 | 32 ± 13 | 33 ± 25 |
Total bilirubin (mg/dL) | 1.1 ± 0.7 | 1.2 ± 0.9 | 1.2 ± 0.5 | 1.2 ± 0.8 |
NT-pro B-type natriuretic peptide (pg/ml) | 6225±5408 | 2903±2820* | 6181±4462 | 5289±5150 |
Albumin (g/dL) | 3.8 ± 0.6 | 3.9 ± 0.6 | 3.7 ± 0.5 | 3.8 ± 0.6 |
Pre-albumin (mg/dL) | 20 ± 7 | 24 ± 9 | 18 ± 7 | 21 ± 7 |
Total cholesterol (mg/dL) | 127 ± 42 | 140 ± 44 | 107 ± 15 | 135 ± 45 |
Uric acid (mg/dl) | 10 ± 6 | 8 ± 3 | 9 ± 3 | 10 ± 6 |
White blood cell count (K/uL) | 7 ± 2 | 7 ± 2 | 7 ± 2 | 7 ± 2 |
Hemoglobin (g/dl) | 13 ± 2 | 13 ± 2 | 13 ± 3 | 13 ± 2 |
Hematocrit (%) | 38 ± 6 | 40 ± 6 | 39 ± 8 | 39 ± 6 |
Platelets (K/uL) | 220 ± 78 | 207 ± 66 | 201 ± 75 | 218 ± 75 |
International normalized ratio | 1.7 ± 0.7 | 1.9 ± 2.3 | 1.6 ± 0.6 | 1.8 ± 1.6 |
Lymphocyte (%) | 20 ± 8 | 25 ± 10* | 19 ± 9 | 22 ± 9 |
Baseline Exercise Testing and Functional Status | ||||
Six Minute Walk (meters) | 207 ± 149 | 173 ± 171 | 180 ± 168 | 199 ± 155 |
Gait speed (meters/second) | 1.0 ± 0.4 | 1.2 ± 0.5* | 0.9 ± 0.2 | 1.0 ± 0.4 |
Peak oxygen uptake VO2 (mL/kg/min) | 11.6 ± 3.4 | 13.4 ± 7.0* | 10.1 ± 1.6 | 12.2 ± 4.7 |
Peak oxygen uptake (%) predicted | 43 ± 12 | 40 ± 18 | 29 ± 11 | 43 ± 13 |
Ventilatory efficiency (VE/VCO2) | 37 ± 11 | 35 ± 8 | 34 ± 1 | 36 ± 11 |
Peak respiratory exchange ratio | 1.1 ± 0.1 | 1.1 ± 0.1 | 1.1 ± 0.2 | 1.1 ± 0.1 |
Echocardiographic and Right Heart Catheterization Hemodynamic Data | ||||
Left ventricular ejection fraction (%) | 21 ± 6 | 22 ± 7 | 21 ± 7 | 21 ± 7 |
LV dimension diastole (cm) | 6.5 ± 0.9 | 6.5 ± 1.0 | 6.6 ± 0.9 | 6.5 ± 0.9 |
Right atrial pressure (mmHg) | 12 ± 6 | 11 ± 6 | 14 ± 6 | 11 ± 6 |
Pulmonary artery systolic pressure (mmHg) | 53 ± 13 | 47 ± 14* | 56 ± 13 | 51 ± 13 |
Pulmonary artery diastolic pressure (mmHg) | 26 ± 7 | 22 ± 9* | 27 ± 8 | 24 ± 8 |
Pulmonary wedge pressure (mmHg) | 22 ± 8 | 19 ± 9 | 23 ± 9 | 21 ± 8 |
Cardiac output (L/min) | 4.4 ± 1.5 | 4.7 ± 1.3 | 3.8 ± 1.8 | 4.6 ± 1.3† |
Cardiac index (L/min/m2) | 2.1 ± 0.7 | 2.3 ± 0.6 | 1.6 ± 0.5 | 2.3 ± 0.7† |
P<0.05 for comparison of Physician Perceived High vs. Low Risk
P<0.05 for comparison of Patient Perceived High vs. Low Risk
P values were not adjusted for multiple comparisons.