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. Author manuscript; available in PMC: 2018 Sep 12.
Published in final edited form as: Lab Chip. 2017 Sep 12;17(18):3120–3128. doi: 10.1039/c7lc00653e

Figure 5. Multiplexed miRNA assay.

Figure 5

(a) Schematic of decoding of shape-encoded microparticles. Particles used for detection of each target miRNA have distinct codes. (b) Multiplexed miRNA assays for three distinctive dysregulation patterns. + and – signs represent 1 amol of spiked-in target and the negative control, respectively. (c) Bright field and fluorescent images of a microfluidic channel for the dysregulation pattern presented in the first row of figure 4b (let7a: +, miR145: +, miR221: -). Scale bars are 50 (b) and 200 µm (c).