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. Author manuscript; available in PMC: 2018 Oct 11.
Published in final edited form as: Neuroscience. 2017 Aug 12;361:129–143. doi: 10.1016/j.neuroscience.2017.08.013

Fig. 8. AIE leads to decreased ChAT+/ nestin+ cell populations in the Nucleus basalis of Meynert (NbM).

Fig. 8

(A) Estimated total number of ChAT+/ nestin− and ChAT+/ nestin+ cells in the NbM. AIE significantly decreased the ChAT+/ nestin+ cell population in the NbM (T; p<0.05). There was a trend for AIE to decrease the estimated ChAT+/ nestin− cell population (t; p=0.08). (B) Number of cells (per mm2) in the NbM. AIE leads to a significant reduction in the total number of cholinergic cells in the NbM (T; p<0.05), and a significant reduction in the number of ChAT+/ nestin+ cells (T; p<0.05). There was a trend in the reduction of ChAT+/ nestin− cells per mm2 as a result of AIE (t; p=.06). (C) Average soma area of ChAT+/ nestin− and ChAT+/ nestin+ cells in the NbM. AIE did not +significantly affect soma area in either cell population.