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. Author manuscript; available in PMC: 2017 Sep 22.
Published in final edited form as: J Burn Care Res. 2015 Jan-Feb;36(1):137–144. doi: 10.1097/BCR.0000000000000164

Figure 2.

Figure 2

The probability of transiting between sleep stages changes following zolpidem administration. The x-axis represents the total duration of the night-time and is scaled from 0 (initial sleeplessness) to 1 (final awakening), as a proportion of the 8-hour study period. Solid black lines depict the predicted transition probabilities within the next 30 seconds for severely burned children who received zolpidem (shaded grey areas represent the 95% confidence intervals). Black arrows indicate the timing of the second administration of zolpidem. Administration of the second dose of zolpidem was associated with an increased likelihood of transitioning from stage 1 to stage 2 sleep. The second dose of zolpidem was also associated with a decrease in the likelihood of waking from stage 1 sleep. In contrast, the second dose of zolpidem was associated with a reduced likelihood of transitioning from stage 1 sleep to slow-wave and rapid eye movement (REM) sleep.