Table 3. Univariate analysis for hospital short-term mortality of patients with acute myocarditis.
Clinical variables | HRs | 95% CI | p Value |
---|---|---|---|
Age (year) | 1.031 | 1.01 to 1.05 | 0.001 |
Males, n (%) | 0.921 | 0.51 to 1.67 | 0.785 |
CK (U/L) | 1.415 | 1.21 to 1.66 | <0.001 |
LDH (U/L) | 1.721 | 1.40 to 2.12 | <0.001 |
ALT (U/L) | 1.373 | 1.21 to 1.55 | <0.001 |
AST (U/L) | 1.500 | 1.32 to 1.71 | <0.001 |
cTnI (ng/ml) | 1.613 | 1.38 to 1.88 | <0.001 |
NT-proBNP (pg/ml) | 1.795 | 1.47 to 2.20 | <0.001 |
CRP (mg/L) | 1.851 | 1.51 to 2.27 | <0.001 |
ESR (mm/H) | 1.039 | 0.83 to 1.30 | 0.739 |
D-dimer (ug/mL) | 1.126 | 1.07 to 1.19 | <0.001 |
HCO3− (mmol/L) | 1.279 | 1.19 to 1.38 | <0.001 |
HCT (%) | 1.068 | 1.02 to 1.12 | 0.009 |
WBC (*109/L) | 1.103 | 1.05 to 1.16 | <0.001 |
PLT (*109/L) | 1.005 | 1.00 to 1.01 | 0.008 |
Serum creatinine (mg/dL) | 3.994 | 2.20 to 7.26 | <0.001 |
BUN (mmol/L) | 1.144 | 1.09 to 1.20 | <0.001 |
eGFR (ml/min/1.73m2) | 1.021 | 1.01 to 1.03 | <0.001 |
UA (umol/L) | 1.003 | 1.00 to 1.00 | <0.001 |
Admission SBP (mmHg) | 1.044 | 1.03 to 1.06 | <0.001 |
Admission DBP (mmHg) | 1.054 | 1.03 to 1.08 | <0.001 |
Hypotension, n (%) | 4.855 | 2.61 to 9.03 | <0.001 |
NYHA (III or IV), n (%) | 9.400 | 4.68 to 18.88 | <0.001 |
LVEF (%) | 1.059 | 1.04 to 1.08 | <0.001 |
Arrhythmia, n (%) | 2.437 | 1.30 to 4.59 | 0.006 |
Temporary pacing, n (%) | 0.701 | 0.20 to 2.46 | 0.579 |
Inotropic agents, n (%) | 0.060 | 0.03 to 0.13 | <0.001 |
IABP support, n (%) | 0.245 | 0.11 to 0.55 | 0.001 |
SOFA score | 1.903 | 1.63 to 2.22 | <0.001 |
APACHE IV score | 1.145 | 1.11 to 1.18 | <0.001 |
SAPS II score | 1.219 | 1.16 to 1.28 | <0.001 |
CK, Creatine Kinase; LDH, Lactate Dehydrogenase; cTnI, cardiac troponin I; NT-proBNP, N-terminal B-type natriuretic peptide; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; HCT, Red blood cell specific volume; WBC, white blood cell; PLT, platelet count; BUN, blood urea nitrogen; eGFR, Estimated glomerular filtration rate; UA, uric acid; SBP, systolic blood pressure; DBP, diastolic blood pressure; Hypotension, MAP (mean arterial pressure) <70 mmHg; LVEF, left ventricular ejection fraction; IABP, intra-aortic balloon pump; SOFA, Sequential Organ Failure Assessment; APACHE IV, Acute Physiology and Chronic Health Evaluation IV; SAPS II, second Simplifed Acute Physiology Score.