Table 4. Multivariate Cox analysis for hospital short-term mortality of patients with acute myocarditis.
| Clinical variables | HRs (95% CI) | p Value |
|---|---|---|
| SOFA | ||
| Model 1 | ||
| SOFA score continuous 1-SD | 1.53 (1.33 to 1.75) | <0.001 |
| Model 2 | ||
| Lower Half (<3) | reference | |
| Upper Half (≥3) | 6.80 (1.85 to 25.01) | 0.004 |
| Model 3 | ||
| Tertile 1 (<2) | reference | |
| Tertile 2 (2∼4) | 3.40 (0.67 to 17.20) | 0.140 |
| Tertile 3 (>4) | 12.16 (2.36 to 62.57) | 0.003 |
| APACHE IV | ||
| Model 1 | ||
| APACHE IV score continuous 1-SD | 1.09 (1.06 to 1.13) | <0.001 |
| Model 2 | ||
| Lower Half (<17) | reference | |
| Upper Half (≥17) | 7.95 (2.25 to 28.16) | 0.001 |
| Model 3 | ||
| Tertile 1 (<11) | reference | |
| Tertile 2 (11∼23) | 4.23 (0.48 to 37.01) | 0.192 |
| Tertile 3 (>23) | 33.86 (4.08 to 280.82) | 0.001 |
| SAPS II | ||
| Model 1 | ||
| SAPS II score continuous 1-SD | 1.14 (1.09 to 1.18) | <0.001 |
| Model 2 | ||
| Lower Half (<14) | reference | |
| Upper Half (≥14) | 7.15 (1.90 to 26.87) | 0.004 |
| Model 3 | ||
| Tertile 1 (<11) | reference | |
| Tertile 2 (11∼17) | 3.90 (0.43 to 35.19) | 0.226 |
| Tertile 3 (>17) | 26.45 (2.82 to 248.10) | 0.004 |
HRs: hazard ratios; CI: confidence interval; SD: standard deviation; SOFA, Sequential Organ Failure Assessment score; APACHE IV, Acute Physiology and Chronic Health Evaluation IV score; SAPS II, second Simplifed Acute Physiology Score. Variables included in the multiple Cox analysis were age, CK, Creatine Kinase, LDH, Lactate Dehydrogenase, cTnI, cardiac troponin I, ALT, alanine aminotransferase, AST, Aspartate aminotransferase, NT-proBNP, N-terminal B-type natriuretic peptide, CRP, C reactive protein, D- dimer, HCO3−, HCT, Red blood cell specific volume, WBC, white blood cell, PLT, platelet count, Serum creatinine, BUN, blood urea nitrogen, eGFR, Estimated glomerular filtration rate, UA, uric acid, SBP, systolic blood pressure, DBP, diastolic blood pressure, NYHA (III or IV), LVEF, left ventricular ejection fraction and Arrhythmia.