Figure 1. shKMT2A effectively downregulates KMT2A expression.
shKMT2A downregulates the expression of KMT2A in U-87 MG cells. (A) Western blot analysis indicated that KMT2A expression was inhibited by shKMT2A-1 and shKMT2A-2, and the result was quantified. shKMT2A-1 was more efficient than shKMT2A-2. (B) RT-PCR demonstrated that shKMT2A inhibits the expression of MLLN and MLLC. *, p < 0.05; **, p < 0.01; ***, p < 0.001.