Table 4. GLIDE docking results for MS-344 and compound 14 at the catalytic site of HDAC8 (PDB ID:1T67).

S. No.	Ligand ID	Docking Score	GLIDE score	Interactions
				Hydrogen Bonds		Interaction with Zn2+
				Backbone	Side Chain
1	MS-344	−7.931	−7.931	His142,His143,Gly151,Gly304;	Asp101, Tyr306;	Ionic interaction
2	14	−7.934	−8.369	Gly140,His142,Gly151,Gly304;	Asp101, Tyr306;	Ionic interaction