(A) Proteins detected in ovarian epithelial carcinomas (OECas), including ovarian serous carcinoma (OSeCa), clear cell carcinoma (OCCCa), endometrioid carcinoma (OEmCa), and mucinous carcinoma (OMuCa), by shotgun proteomics analysis. (B) Upper: staining is by hematoxylin and eosin (HE) and immunohistochemistry (IHC) for LEFTY in OECas. Note the diffuse distribution of strong cytoplasmic LEFTY-positive cells in OCCCa, in contrast to a sporadic or absent distribution in non-OCCCa. Enclosed boxes in panels (a) are magnified in panels (b). Original magnification, x100 and x400 (inset). Lower: IHC score for LEFTY in OECas. Hist, histology; No., number (C) LEFTY expression detected by western blot assay in OECas. Note the precursor (42 kDa) and the cleaved forms (34 and 28 kDa).