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. 2017 Jul 18;8(38):64066–64082. doi: 10.18632/oncotarget.19318

Figure 2. PD-1, PD-L1, and PD-L2 expression in TCs and TIICs of GC patients.

Figure 2

Routine H&E staining (A, C, E, G, I, K and O). (B) Positive PD-1 expression in the lymph follicles (IHC). (D) Positive PD-L1 expression in tumor cells with a ‘diffuse type’ phenotype (IHC). (F) Positive PD-L1 expression at the interface between tumor and non-neoplastic tissues (IHC). (H) Positive PD-L2 expression in the tumor cells (IHC). (J) Positive PD-L1 expression in the TIICs (IHC). (L) Positive PD-L2 expression in the TIICs (IHC). (M) Positive PD-L1 expression in the neoplastic nerve fibers (IHC). (N) Positive expression of PD-L2 in the intestinal metaplasia of gastric epithelium (IHC). (P) Positive detection of EBV in tumor microarrays of gastric cancer (IHC). Magnification: 200× (A-L), 400× (M-N), and 100× (O-P).