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. 2017 Jul 18;8(38):64114–64128. doi: 10.18632/oncotarget.19342

Figure 4. Effects of miR-708 on the expression of proteins related to the cell cycle and apoptosis as determined by western blotting.

Figure 4

(A and D). The miR-708 inhibitor decreased cyclin D1 expression in BALL-1 (A) and Nalm-6 (D) cells. (B-F) The miR-708 inhibitor significantly increased Bax expression and strongly decreased Bcl-2 expression in BALL-1 (B and C) and Nalm-6 cells (E and F). Non-transfected cells were used as controls. The fold changes in the relative protein levels were calculated with reference to the control levels. The data are presented as the means ± SDs (n=3, * P<0.05; ** P<0.01). (G and H). The images represent the results of a western blotting analysis of cyclin D1, Bax and Bcl-2 protein expression.