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. 2017 Jul 18;8(38):64180–64190. doi: 10.18632/oncotarget.19419

Table 1. The single-nucleotide polymorphisms (SNPs) analyzed in this study.

Class SNP Position (hg38) (bp) Candidate gene Allele Minor allele frequencies (MAF) HWE
Major Minor EUR JPT TWB
1 rs11900673 chr2:62225526 B3GNT2 C T 0.13 0.33 0.18 0.28
1 rs657075 chr5:132094425 CSF2 G A 0.13 0.38 0.25 0.46
1 rs12529514 chr6:14096427 CD83 T C 0.06 0.13 0.23 0.78
1 rs2233434 chr6:44265183 NFKBIE T C 0.04 0.22 0.16 0.52
1 rs10821944 chr10:62025330 ARID5B T G 0.31 0.33 0.27 0.59
1 rs3781913 chr11:72662452 PDE2A-ARAP1 A C 0.56 0.29 0.28 0.74
1 rs2841277 chr14:104924668 PLD4 T C 0.52 0.30 0.42 0.24
1 rs2847297 chr18:12797695 PTPN2 A G 0.32 0.35 0.30 0.29
2 rs11209032 chr1:67274409 IL23R G A 0.33 0.41 0.49 0.86
2 rs4672495 chr2:62294109 T G 0.32 0.12 0.17 0.86
2 rs10865331 chr2:62324337 G A 0.38 0.27 0.49 0.60
2 rs27434 chr5:96793809 ERAP1 A G 0.79 0.52 0.47 0.40
2 rs3734523 chr6:25925759 SLC17A2 G A 0.09 0.00 0.03 0.38
2 rs13202464 chr6:31376806 HLA-B A G 0.06 0.18 0.07 0.55
2 rs13210693 chr6:109277761 G A 0.53 0.56 0.48 0.97

EUR, European; JPT, Japanese in Tokyo; TWB, Taiwan biobank; HWE, p value for Hardy-Weinberg equilibrium test in TWB.

SNPs of class 1 and class 2 were extracted from Okada et al. (2012) [21] and Wen et al. (2014) [29], respectively.

MAFs of EUR and JPT were extracted from NCBI; MAFs of TWB were obtained from the Taiwan View website (https://taiwanview.twbiobank.org.tw/index). Miner allele was determined by MAF of TWB.