Table 2. Percentage of cases with various PD-L1 expression on tumor cells visualized by immunohistochemistry method, using different clones of monoclonal antibodies against PD-L1 molecule.
Monoclonal antibody clone used for slide staining | <1 % TPS | ≥1 % TPS | <5% TPS | ≥5% TPS | <50% TPS | ≥50% TPS |
---|---|---|---|---|---|---|
22C3, n(%) | 13 of 48 (27.1) | 35 of 48 (72.9) | 16 of 48 (33.3) | 32 of 48 (66.7) | 26 of 48 (54.2) | 22 of 48 (45.8) |
SP 142, n(%) | 19 of 48 (39.6) | 29 of 48 (60.4) | 29 of 48 (60.4) | 19 of 48 (39.6) | 37 of 48 (77.1) | 11 of 48 (22.9) |
Chi-square: | 1.688 | 7.069 | 5.587 | |||
p-value: | 0.1939 | 0.0078 | 0.018 |