Table 4. Percentage of cases with various PD-L1 expression on tumor cells visualized by immunohistochemistry method, using SP142 monoclonal antibody in patients with different clinical characteristics.

Clinical characteristic	<1 % TPS	≥1 % TPS	<5% TPS	≥5% TPS	<50% TPS	≥50% TPS
Male, n(%)	7 (35)	13 (65)	10 (50)	10 (50)	14 (70)	6 (30)
Female, n(%)	12 (42.9)	16 (57.1)	19 (67.9)	9 (32.1)	23 (82.1)	5 (17.9)
Chi-square:	0.301		1.556		0.974
p-value:	0.5833		0.2123		0.3237
<67 years old, n(%)	12 (46.2)	14 (53.8)	17 (65.4)	9 (34.6)	19 (73.1)	7 (26.9)
≥67 years old, n(%)	7 (31.8)	15 (68.2)	12 (54.5)	10 (45.4)	18 (75)	4 (25)
Chi-square:	1.024		0.585		0.515
p-value:	0.3116		0.4444		0.4730
Smokers, n(%)	12 (32.4)	25 (67.6)	22 (59.5)	15 (40.5)	32 (86.5	5 (13.5)
Non-smokers, n(%)	7 (63.6)	4 (36.4)	7 (63.6)	4 (36.4)	8 (72.7)	3 (27.3)
Chi-square:	3,452		0.062		1,156
p-value:	0.0631		0.8034		0.2823
SCC, n(%)	3 (21.4)	11 (78.6)	4 (28.6)	10 (71.4)	8 (57.1)	6 (42.9)
Non-SCC, n of 48 (%)	16 (47.1)	18 (52.9)	25 (73.5)	9 (26.5)	29 (85.3)	5 (14.7)
Chi-square:	2.724		7.603		4.449
p-value:	0.0989		0.0058		0.0349
Early stages (I-IIIA), n(%)	13 (38.2)	21 (61.8)	22 (64.7)	12 (35.3)	28 (82.4)	6 (17.6)
Advanced stages (IIIB-IV), n(%)	6 (42.9)	8 (57.7)	7 (50)	7 (50)	9 (64.3)	5 (35.7)
Chi-square:	0.089		0.897		1.832
p-value:	0.7655		0.3436		0.1759
FFPE tissue, n(%)	16 (37.2)	27 (62.8)	26 (60.5)	17 (39.5)	32 (74.4)	11 (25.6)
Cellblock, n(%)	3 (60)	2 (40)	3 (60)	2 (40)	5 (100)	0 (0)
Chi-square:	0.973		0		1.659
p-value:	0.3239		1		0.1977
EGFR wt, n(%)	15 (36.6)	26 (63.4)	24 (58.5)	17 (41.5)	31 (75.6)	10 (24.4)
EGFR mut., n(%)	4 (57.1)	3 (42.9)	5 (71.4)	2 (28.6)	6 (85.7)	1 (14.3)
Chi-square:	1.057		0.416		0.346
p-value:	0.3039		0.5189		0.5564
No ALK rearrangement, n(%)	17 (38.6)	27 (61.4)	26 (59.1)	18 (40.9)	33 (75)	11 (25)
ALK rearrangement, n(%)	2 (66.7)	1 (33.3)	3 (100)	0 (0)	3 (100)	0 (0)
Chi-square:	0.916		1.989		0.979
p-value:	0.3385		0.1584		0.3224