Table 2. The result of meta-regression.

Sensitivity
Parameter	Estimate(95%CI)	Coef	Z	P>|z|
Detection method	0.68 [0.62 - 0.74]	0.76	−0.52	0.60
Region	0.58 [0.49 - 0.67]	0.34	−2.82	0.00*
Cut-off	0.68 [0.62 - 0.74]	0.77	−0.05	0.96
Sample size#	0.71 [0.62 - 0.78]	0.87	0.65	0.51
Specificity
Parameter	Estimate(95%CI)	Coef	Z	P>|z|
Detection method	0.92 [0.89 - 0.94]	2.44	−0.29	0.77
Region	0.89 [0.83 - 0.94]	2.13	−1.40	0.16
Cut-off	0.92 [0.89 - 0.95]	2.50	0.30	0.77
Sample size#	0.90 [0.84 - 0.93]	2.15	−1.75	0.08
Joint model
Parameter	I-squared(95%CI)	LRTChi	P Value
Detection method	0.00 [0.00 - 100.00]	0.82	0.66
Region	85.04 [68.84- 100.00]	13.37	0.00*
Cut-off	94.18 [89.24 - 99.13]	34.38	0.00*
Sample size#	32.77 [0.00 - 100.00]	2.97	0.23

^{#Total patient <150 cases or ≥150 cases;* P<0.05}.