Table 2. Adverse events in the Apatinib treatment.

Adverse event	Grade 1* (n, %)	Grade 2 (n, %)	Grade 3 (n, %)	Total
Neutropenia	2(12.5)	1(6.3)	-	3(18.8)
Thrombocytopenia	2(12.5)	-	-	2(12.5)
Bilirubin increased	2(12.5)	1(6.3)	-	3(18.8)
Transaminase increased	1(6.3)	1(6.3)	-	2(12.5)
Hematuria	1(6.3)	-	-	1(6.3)
Proteinuria	2(12.5)	4(25.0)	1(6.3)	7(43.8)
Hypertension	1(6.3)	1(6.3)	3(18.7)	5(31.3)
Hand-foot syndrome	1(6.3)	4(25.0)	2(12.5)	7(43.8)
Pain	2(12.5)	2(12.5)	-	4(25.0)
Fatigue	1(6.3)	1(6.3)	-	2(12.5)
Mucositis	-	2(12.5)	-	2(12.5)
Anorexia	-	1(6.3)	-	1(6.3)
Dizziness	1(6.3)	-	-	1(6.3)
Fever	1(6.3)	-	-	1(6.3)
Diarrhea	1(6.3)	-	-	1(6.3)