Table 1. Comparisons of baseline clinicopathological features based on NC and NP in cohort 1 (N=378).
| Clinicopathological features | N (%) | NC | P value | NP | P value | ||
|---|---|---|---|---|---|---|---|
| LNC(n= 254) | HNC(n= 122) | LNP(n= 297) | HNP(n= 81) | ||||
| Age(Mean±SD) | 378 | 63.78±12.74 | 63.07±12.97 | 0.6108 | 63.58±13.03 | 63.41±12.00 | 0.9133 |
| Gender | 0.1012 | 0.1886 | |||||
| Male | 209(55.29%) | 133(52.36%) | 76(61.29%) | 159(53.54%) | 50(61.73%) | ||
| Female | 169(44.71%) | 121(47.64%) | 48(38.71%) | 138(46.46%) | 31(38.27%) | ||
| Tumor stage | 0.1042 | 0.0394 | |||||
| III | 23(6.08%) | 19(7.48%) | 4(3.23%) | 22(7.41%) | 1(1.23%) | ||
| IV | 355(93.92%) | 235(92.52%) | 120(96.77%) | 275(92.59%) | 80(98.77%) | ||
| Primary tumor site | 0.5800 | 0.6654 | |||||
| Gastrointestinal tumors | 198(52.38%) | 131(51.57%) | 67(54.03%) | 152(51.18%) | 46(56.79%) | ||
| Thoracic cancers | 86(22.75%) | 55(21.65%) | 31(25.00%) | 71(23.91%) | 15(18.52%) | ||
| Urogenital neoplasms | 59(15.61%) | 45(17.72%) | 14(11.29%) | 48(16.16%) | 11(13.58%) | ||
| Head and neck neoplasm | 16(4.23%) | 11(4.33%) | 5(4.03%) | 11(3.70%) | 5(6.17%) | ||
| Other tumors | 19(5.03%) | 12(4.72%) | 7(5.65%) | 15(5.05%) | 4(4.94%) | ||
| Palliative care | 0.7042 | 0.7292 | |||||
| PCR | 279(73.81%) | 189(74.41%) | 90(72.58%) | 218(73.40%) | 61(75.31%) | ||
| BSC | 99(26.19%) | 65(25.59%) | 34(27.42%) | 79(26.60%) | 20(24.69%) | ||
| Family history | 0.6376 | 0.6156 | |||||
| No | 264(70.78%) | 181(71.54%) | 83(69.17%) | 207(70.17%) | 57(73.08%) | ||
| Yes | 109(29.22%) | 72(28.46%) | 37(30.83%) | 88(29.83%) | 21(26.92%) | ||
| Unknown | 5 | ||||||
| ECOG score | 0.0107 | 0.0005 | |||||
| <3 | 218(57.67%) | 158(62.20%) | 60(48.39%) | 185(62.29%) | 33(40.74%) | ||
| >=3 | 160(42.33%) | 96(37.80%) | 64(51.61%) | 112(37.71%) | 48(59.26%) | ||
| Comorbidity | 0.9782 | 0.6208 | |||||
| No | 229(60.58%) | 154(60.63%) | 75(60.48%) | 178(59.93%) | 51(62.96%) | ||
| Yes | 149(39.42%) | 100(39.37%) | 49(39.52%) | 119(40.07%) | 30(37.04%) | ||
| Nutritional status | 0.5897 | 0.0831 | |||||
| Normal | 107(28.31%) | 76(29.92%) | 31(25.00%) | 91(30.64%) | 16(19.75%) | ||
| Abnormal | 268(70.90%) | 176(69.29%) | 92(74.19%) | 204(68.69%) | 64(79.01%) | ||
| Unknown | 3(0.79%) | 2(0.79%) | 1(0.81%) | 2(0.67%) | 1(1.23%) | ||
Abbreviation: NC, neutrophil counts; NP, neutrophil percentages; SD, Standard Deviation;
LNC, low NC (pretreatment NC<=8); HNC, high NC (pretreatment NC>8); LNP, low NP (pretreatment NP<=0.85); HNP, high NP (pretreatment NP>0.85); BSC, best supportive care; PCR, palliative chemoradiotherapy; ECOG, Eastern Cooperative Oncology Group