Appendix 2—video 4. 3D modeling of dorsal-ventral HF wave interaction.
Download video file (4.2MB, mp4)
Initial head-to-tail asynchrony in the dorsal domain was introduced by assigning a group of HFs on one end with a one-time increase in activator ligands. We also block ventral HF growth until t = 14 to simulate the temporal-advancement in dorsal domain. Ventral HFs has faster cycle than dorsal HFs. Simulations reproduce head-to-tail asynchrony of first two cycles, which degrades into spontaneous waves possessing bilateral symmetries in later cycles, similar to what is observed from experiments. Also see Figure 2F.