Appendix 2—table 4.

Activity strength of activator/inhibitor ligands (L), antagonists (A), receptors (R) and ligand-bond receptors (LR) in different phases within a full HF growth cycle.

DOI: http://dx.doi.org/10.7554/eLife.22772.082

		Activator		Inhibitor
		Region I	Region II	Region I	Region II
		(Bulge)	(sHG, Matrix, DP)	(Bulge)	(sHG, Matrix, DP)
Late Competent Telogen (late C)	L	3	(3,0,4)	2	(2,0,3)
	A	2	(2,0,1)	0	(0,0,3)
	R	2	(2,0,4)	3	(3,0,3)
	LR	4	(4,0,4)	1	(1,0,3)
Propagating Anagen (P)	L	2	(0,4,4)	2	(0,3,3)
	A	2	(0,2,3)	0	(0,2,2)
	R	2	(0,3,4)	3	(0,3,3)
	LR	4	(0,4,4)	1	(0,3,3)
Autonomous Anagen (A)	L	2	(0,4,4)	2	(0,4,4)
	A	2	(0,4,4)	0	(0,2,2)
	R	2	(0,3,4)	3	(0,3,3)
	LR	2	(0,4,4)	3	(0,3,3)
Catagen (Cat)	L	2	(2,0,2)	2	(2,0,4)
	A	2	(2,0,4)	0	(0,0,1)
	R	2	(2,0,4)	3	(3,0,3)
	LR	1	(1,0,1)	3	(3,0,3)
Refractory Telogen (R)	L	2	(2,0,1)	2	(2,0,4)
	A	2	(2,0,4)	0	(0,0,1)
	R	2	(2,0,4)	3	(3,0,3)
	LR	1	(1,0,1)	4	(4,0,4)
Early Competent Telogen (early C)	L	Similar to refractory telogen		Similar to late competent telogen
	A
	R
	LR