Table 3.
code | antigen | antibody | epitope | refs |
---|---|---|---|---|
| ||||
2w9e | huPrP (119–231) | ICSM 18 Fab | (H1, 143–156) | [63] |
| ||||
1tpx | OvPrPC and OvPrPSC | VRQ14 Fab | 188–199 | [64] |
(114–234) | ||||
1. A136-R154-R171 | ||||
2. V136-R154-Q171 | ||||
3. A136-R154-Q171 | ||||
| ||||
4DGI | huPrPc (120–230) | POM1 Fab | Primary: (residues 140–147) | [65] |
Secondary: Lys204, Arg208 and Gln212 | ||||
| ||||
4YX2 | boPrP(103–242), | POM1 Fab | The same with huPrP | [66] |
4YXH | dePrP (123–231), | |||
4YXK | ekPrP (124–231) , | |||
4YXL | shPrP (90–230) | |||
| ||||
4j8r | Peptide OR2 | POM2 Fab | PHGGSWGQPHGGSWGQ | [62] |
PHGGSWGQPHGGS WGQ | ||||
| ||||
1cr9 | peptide epitope (SHaPrP 104–113) | 3F4 Fab | KPKTNMKHMA | [61] |
| ||||
4kml | full-length HuPrP | nanobody (Nb484) | discontinuous epitope including residues | [67] |
123–125 in the β0-β1 loop, residues 164–170 in the β2-α2 | ||||
loop, and residues | ||||
174–185 in the α2-helix. |