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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Biochimie. 2017 Jun 16;141:86–90. doi: 10.1016/j.biochi.2017.06.010

Figure 4. Model of lipid mediator regulation of experimental Lyme arthritis.

Figure 4

Following infection both pro-and anti-inflammatory mediators are produced and inflammation ensues. As the spirochetes are cleared by antibody and innate immune cells, other pro-resolution lipid mediators are produced which stimulate resolution and a return of the tissue to homeostasis. Figure is adapted with permission from [15].